EVALUATION OF THE HEMOSTATIC ACTIVITY OF HEMOBEN IN THE MODEL OF SPLEEN INJURY ON HYPOCOAGULATION

Abstract

The article presents data on a new model of spleen injury reconstruction in experimental animals with active bleeding, which without therapeutic measures, recurs and leads to death. To assess the possibility of bleeding control from the spleen wound under drug hypocoagulation additional experiments were carried out using domestic local hemostatic preparations: hemosponges obtained from animal collagen and a hemostatic implant in the form of Hemoben powder. It has been proven, in case of spleen injury on hypocoagulation, hemosponge is ineffective, while Hemoben allows achieving hemostasis; however, the recurrence rate can increase up to 20% depending on the degree of the spleen capsule damage.