LIPID METABOLISM DISORDERS AND ITS CORRECTION IN CHRONIC KIDNEY DISEASE

Keywords

chronic kidney disease, cholesterol, triglycerides, low density lipoproteins, high density lipoproteins, apo AI, apo AII, lipoprotein lipase, hepatic triglyceride lipase, statins, fibrates, nicotinic acid

Abstract

Chronic kidney disease — a proven risk factor of the development and progression of lipid metabolism disorders. The basis of these disorders — an increase in blood plasma cholesterol, triglycerides, low density lipoproteins and decreased levels of high density lipoproteins, apo AI and apo AII. There has been a decrease in the activity of enzymes: lipoprotein lipase, hepatic triglyceride lipase, lecithin-cholesterol acyltransferase. The use of lipidmodifying drugs — statins, fibrates, nicotinic acid was proposed.

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