Abstract
To select an antiulcer therapy scheme, 36 patients with duodenal ulcer were observed, the average age was 16 ± 1 years, the size of the ulcer in the examined patients was from 0.5 to 1.2 cm. Blood ELISA was used to detect Helicobacter pylori. Depending on the nature of the therapy, the patients were divided into 2 groups; patients of the 1st (main) group (H=26) received nolpaza 40 mg once a day for 6 weeks, fromilid 500 mg x 2 times a day for 7 days, azit 500 mg x 1 time a day for 3 days. The comparison group (2nd) consisted of 10 patients who received three-component therapy (omeprazole 20 mg 2 times, metronidazole 250 mg 1 t x 3 times and amoxacillin 1000 mg x 2 times a day) for 7 days. Thus, eradication therapy has been and remains not only an effective treatment for duodenal ulcer, but also an effective way to prevent recurrence, which is of great importance for reducing public costs. The use of nolpaza 40 mg + fromilid 500 mg 2 times, azit 500 mg x 1 time per day for 3 days with duodenal ulcer is effective, safe, and economically justified.