Keywords
Abstract
The review analyzes current ideas about the mechanisms of liver fibrosis formation in chronic diffuse liver diseases. The relevance and clinical significance of assessing the degree of fibrosis is shown, methods for early diagnosis of liver fibrosis and its progression are indicated. It is known that in many countries of the world there is a high incidence of chronic viral hepatitis B and C. Early diagnosis of liver cirrhosis and assessment of the severity of liver fibrosis in chronic hepatitis remains an urgent task of modern health care. However, liver biopsy, which is considered the “gold standard” for determining the nature of the pathological process in the liver, is often impossible due to the severity of the underlying or concomitant diseases, and sometimes accompanied by serious complications. In connection with these complexities, there is an urgent need to develop non-invasive methods for diagnosing fibrosis and cirrhosis of the liver.