Keywords
Abstract
40 patients with gout (7 females and 33 males) were included in the study to assess the rate of onset of the analgesic effect of a non-steroidal anti-inflammatory drug (NSAID). The patients were divided into 2 groups. The 1st main group included 20 patients with gout who received tablet namesulide (drug "Aponil") 100 mg 2 times a day. To compare the effectiveness of nimesulide, patients of group 2 (control group) were given a drug from the group of non-selective NSAIDs - diclofenac sodium 75 mg 2 times a day. The duration of the drugs was 7 days. The most effective in terms of the speed and severity of the analgesic effect was nimesulide in tablet form, since after 20 minutes - in 7, after 40 minutes - in 13 patients pain in the joints decreased, and after an hour 16 patients of the 1st group rated the effect as good, while in 6 of them the pain decreased significantly. In the 2nd group, only 3 patients indicated any decrease in pain only after 1-1.5 hours. Thus, in group 1, all patients noted the analgesic and anti - inflammatory effect of nimesulide tablets. In group 2, only two patients noted the effect of diclofenac. Nimesulide stopped an attack of arthritis in 9 (45%) patients of the 1st group, in 2 (10%) - of the 2nd group.