Keywords
Hepcidin, liver hemosiderosis, anemia of chronic diseases, viral hepatitis B and C
Abstract
Many chronic human diseases are accompanied by the so-called anemia of chronic disease (ACD), the key mediator of which is hepcidin, an iron-regulatory polypeptide hormone of the liver. ACB is considered as one of the fundamental reactions of innate immunity directed at increasing the overall resistance of the organism. Recall also that hepcidin has a direct antimicrobial effect by destroying bacterial membranes.