Common neurohormonal mechanisms in the development of enteropathy and metabolic syndrome (MS). MS is characterized by an increase in visceral fat mass, decreased sensitivity of peripheral tissues to insulin and hyperinsulinemia, which cause disorders of carbohydrate, lipid, purine metabolism and hypertension. This is associated to some extent with the presence of common neurohormonal mechanisms in the development of enteropathy and MS. The paper gives the physical, laboratory and instrumental methods for identifying SI dysfunctions in patients with MS. Therapy for the latter is of particular interest in the context of SB functional recovery. The authors discuss the possibilities of enteropathy therapy in patients with MS; thus there is not only SI functional recovery, but also improved overall metabolic processes.