. It was found that in patients with type 2 diabetes mellitus against the background of normal body weight, the average level of adiponectin (AN) in blood plasma, unlike patients with overweight and obesity, is within the reference norms. At the same time, about half of them (54.5%) have a reduced AH level. The subgroup with a reduced level of AH is characterized by a large age of patients and the duration of diabetes, as well as an increase in the levels of triglycerides and very low-density lipoproteins, a more frequent increase in waist circumference. At the same time, in patients with type 2 diabetes mellitus with normal body weight, there were no significant associative links between the level of AN and indicators of carbohydrate metabolism - blood glucose and fasting insulin levels, the NOMA-IR index. The obtained data substantiate the need to timely identify and correct lipid metabolism disorders in patients with type 2 diabetes mellitus with normal body weight.