Keywords
ulcerative colitis, TGF-β2, IL-6, IL-17A, TGF-β2
Abstract
The study included 128 patients treated ulcerative colitis in the Gastroenterology Department of Bukhara regional Multidisciplinary Medical Center during 2021-2023 and 20 health professionals as a control group. Patients were diagnosed with serum immunoferment analysis using TNF-α, IL-6, IL-17A, TGF-β2 and its importance was studied. The results of the study showed an increase in TNF- α, IL-6, IL-17A and a decrease in TGF-β2 in severe types of ulcerative colitis, and found that it could be used in diagnosis as a poor prognostic marker.