Objective of the study. Analysis of the relationship between the resistance indices (IR) of the main and intrarenal renal arteries, measured by ultrasound Doppler ultrasound (DUS), and clinical and laboratory data, as well as the identification of their prognosis in assessing the progression of chronic kidney disease (CKD).
Materials and methods. The study included 106 patients with CKD, divided into groups with glomerular or interstitial diseases. At the first hospitalization, the glomerular filtration rate (GFR) calculated using the CKD-EPI formula, the degree of proteinuria (PU), the size of the kidneys, the thickness of the renal parenchyma and the parenchymopielic index, IR of the main and intrarenal vessels were determined. The average duration of observation of patients was 12 ± 2.64 months. Upon readmission, the rate of GFR decline was analyzed.
Results. IR of the main and intraparenchymal vessels depends on the patient's age and pulse pressure. In the group of patients with glomerular diseases, IRs are associated with GFR and PU, while in the group of interstitial diseases, with the size and structure of the kidneys. IR of interlobar arteries (MA) is the most sensitive predictor of deterioration of renal function with a cut-off value of 0.65, comparable to the predictive value of PU.
Conclusion. Indicators of the resistance index of vasorenal vessels in the main and intraparenchymal vessels can be considered as a predictor of the progression of renal function.