Obesity is a recurrent polyetiological disease. 30-60% of women of reproductive age are overweight, and 25-27% are obese. By 2025, 50% of the world's women are expected to be obese. Obesity in women of reproductive age is accompanied by a high frequency of anovulation, hyperandrogenism syndrome, menstrual irregularities, endometrial pathology, infertility. During pregnancy, this group of women has a higher risk of loss in the short term, including pregnancy as a result of assisted reproductive technologies. An increase in body weight and the development of obesity can lead to decreased fertility in women. The body mass index of a woman of reproductive age negatively affects the course of pregnancy, namely: the risk of gestational diabetes, increased blood pressure, eclampsia, pathological course of labor, and pathology of the newborn increases. Obesity is a woman of reproductive age is an independent risk factor for cancer: breast cancer and endometrial cancer, and also leads to a decrease in the survival rate for ovarian cancer. Obesity often accompanies polycystic ovary syndrome, which occurs in every 10th patient of reproductive age. The combination of these diseases increases the risk of cardiometabolic conditions such as impaired glucose tolerance, type 2 diabetes, and dyslipidemia. Weight loss in such patients is a necessary component of complex therapy aimed at improving reproductive potential.